The antibody detects: Human CD71 To insure lot-to-lot consistency, each batch of product is tested by flow cytometry to conform with the characteristics of a standard reference reagent.
Working Dilution: <= 1 µg/10^6 cells Representative data are included in this product insert.
Each laboratory should determine an optimum working titer for use in its particular application. Other applications have not been tested but use in such assays should not necessarily be excluded.
Volume d'échantillon
1 mL
Restrictions
For Research Use only
Agent conservateur
Azide free
Conseil sur la manipulation
Each reagent is stable for the period shown on the bottle label if stored as directed.
Stock
-20 °C
Stockage commentaire
Aliquot and freeze the low endotoxin, azide-free product at -20 °C immediately upon receipt.
CD71 is a 95 kDa type II heterodimeric transmembrane glycoprotein that is the receptor for transferrin. CD71 expression is very low on resting leukocytes but is upregulated upon activation. CD71 plays a critical role in cell proliferation by controlling the supply of iron, which is essential for many metabolic pathways, through the binding and endocytosis of transferrin.